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Association of Calpain 1 (CAPN1) and HRSP12 allelic variants in beef cattle with carcass traits
Author(s) -
Hou Guanyu,
Meng Huang,
Xue Gao,
Junya Li,
Gao Huijiang,
Ren Hong-yan,
ShangZhong Xu
Publication year - 2011
Publication title -
african journal of biotechnology
Language(s) - English
Resource type - Journals
ISSN - 1684-5315
DOI - 10.5897/ajb11.338
Subject(s) - marbled meat , tenderness , meat tenderness , biology , genetics , quantitative trait locus , beef cattle , single nucleotide polymorphism , allele , trait , candidate gene , genotype , gene , zoology , computer science , programming language
Calpain 1 (CAPN1) and its activator HRSP12 are evaluated as candidate gene for quantitative trait loci (QTLs) affecting meat tenderness. In this study, SNPs were detected by sequencing in 323 cattle from 9 breeds. The association results showed that the A3553G and T824C loci individually related with marbling and tenderness, and CAPN1/HRSP12 double homozygote and heterozygote/homozygote pairs (AA/TT, AA/CC, AG/TT and GG/TT) had higher marbling score than the other groups. Our findings suggest that polymorphisms in CAPN1 and HRSP12 might be the important genetic factor influencing meat quality in carcass trait. Key words : Cattle, Calpain 1, HRSP12, association, carcass trait.

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