Antioxidant, antibacterial and -glucosidase inhibitory activities of different extracts of Cortex Moutan | Zendy

Jinfeng Yang | Zendy; Kim Ju Sung | Zendy; Jin Sa Yeo | Zendy; Ok Kim Myeong | Zendy; Ju Jeong Hyun | Zendy; Yeon Yu Chang | Zendy; Jo Kim Myong | Zendy

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Antioxidant, antibacterial and -glucosidase inhibitory activities of different extracts of Cortex Moutan

Author(s) -

Jinfeng Yang,

Kim Ju Sung,

Jin Sa Yeo,

Ok Kim Myeong,

Ju Jeong Hyun,

Yeon Yu Chang,

Jo Kim Myong

Publication year - 2011

Publication title -

african journal of biotechnology

Language(s) - English

Resource type - Journals

ISSN - 1684-5315

DOI - 10.5897/ajb11.1115

Subject(s) - chemistry , dpph , paeonol , antioxidant , ethyl acetate , antibacterial activity , ic50 , acetone , chromatography , traditional medicine , organic chemistry , bacteria , biochemistry , medicine , in vitro , biology , alternative medicine , pathology , genetics

Different extracts of Cortex Moutan (CM) were investigated for their antioxidant, antibacterial and αglucosidase inhibitory activities. The content of paeonol was quantified by high performance liquid chromatography (HPLC). The results show that the yield of acetone extract (57.14%) was significantly higher than those of other solvents. The ethyl-acetate extract exhibited maximum paeonol concentration (60.69 μg/ml), good antibacterial activities (MIC = 100 μg/ml) against Escherichia coli and possessed significant α-glucosidase inhibitory activity. In addition, among all of the extracts, ethylacetate extract demonstrated a high total phenolic value of 127.12 ± 1.42 mg GAE/g, high DPPH radical scavenging activity with an IC50 of 19.88 ± 0.26 μg/ml, and significant reducing power, suggesting that CM is a potential source of natural antioxidants.

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