Analysis of the essential oil from the leaves of Sesamum radiatum, a potential medication for male infertility factor, by gas chromatography - mass spectrometry

Essential oil was extracted from the dried leaves of Sesamum radiatum by hydro-distillation and analyzed by combined gas chromatography-mass spectrometry. n-Hexadecanoic acid was found to be the major constituent and with three other fatty acids namely, 9,12,15-octadecanoic acid-(Z,Z,Z), dodecanoic acid and tetradecanoic acid constitute 40.64% of the oil. Other constituents include heptatriacontanol, estra–1,3,5(10)–trien-17a-ol, 1-(+)–ascorbic acid, 2,6-dihexadecanoate, ethyl isoallocholate, 18,19–secoyohimban–19-oic acid, 16,17,20,21-tetrahydro-16-(hydroxymethyl)-methyl ester, (15a, 16E)-trans-(2,3-diphenylcyclopropyl) methylphenyl sulfoxide, 1,1-[2-methyl-2-(phenylthio) cyclopropylidene]bis-benzene and phenolics. The presence of some of these constituents in the essential oil provides the scientific evidences for the observed cardiovascular and estrogenic activity as well as curative properties of the plant for male infertility factor, constipation, fungal and bacterial infections and bruises.