Open AccessThe relationship between platelet endothelial cell adhesion molecule-1 and paraquat-induced lung injury in rabbits
Author(s) -
Jing Shi,
Chunlin Hu,
Yufeng Gao,
Xiao-xing Liao,
Huilin Xu
Publication year - 2012
Publication title -
world journal of emergency medicine
Language(s) - English
Resource type - Journals
ISSN - 1920-8642
DOI - 10.5847/wjem.j.issn.1920-8642.2012.01.011
Subject(s) - medicine , cd31 , lung , angiogenesis , immunohistochemistry , pathology , pulmonary fibrosis , fibrosis , andrology , paraquat , platelet , endothelial stem cell , chemistry , in vitro , biochemistry
Platelet endothelial cell adhesion molecule-1 (PECAM-1), also known as CD31, is mainly distributed in vascular endothelial cells. Studies have shown that PECAM-1 is a very significant indicator of angiogenesis, and has been used as an indicator for vascular endothelial cells. The present study aimed to explore the relationship between the expression of PECAM-1 and the degree of acute lung injury (ALI) and fibrosis in paraquat (PQ) induced lung injury in rabbits.