Analysis of Tandem Repeat Patterns in Nlrc4 using a Motif Model
Author(s) -
Sim-Hui Tee
Publication year - 2012
Publication title -
international journal of information technology and computer science
Language(s) - English
Resource type - Journals
eISSN - 2074-9015
pISSN - 2074-9007
DOI - 10.5815/ijitcs.2013.01.06
Subject(s) - motif (music) , computer science , tandem , tandem repeat , biology , genetics , materials science , genome , composite material , gene , physics , acoustics
Exponential accumulation of biological data requires computer scientists and bioinformaticians to improve the efficiency of computer algorithms and databases. The recent advancement of computational tools has boosted the processing capacity of enormous volume of genetic data. This research applied a computational approach to analyze the tandem repeat patterns in Nlrc4 gene. Because the protein product of Nlrc4 gene is important in detecting pathogen and triggering subsequent immune responses, the results of this genetic analysis is essential for the understanding of the genetic characteristics of Nlrc4. The study on the distribution of tandem repeats may provide insights for drug design catered for the Nlrc4-implicated diseases.
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