Dynamic Characteristics of the Hippocampal Neuron under Conductance's Changing

The hippocampal CA1 pyramid neuron has plenty of discharge actions. In the thesis, the dynamic characteristics of the hippocampal neuron model are analyzed and discussed by the neurodynamic theory and methods. Under a certain amplitude current’s stimulation, the change of (the maximum conductance of the transient sodium channel) and (the maximum conductance of the delay rectification potassium channel) can cause different dynamic characteristics of the neuron model. The transient Na current( ) caused by is indispensable in the discharge’s formation process of the model. The model can generate the discharge process only when reaches a certain threshold. In the discharge process of the neuron model, ’s changing affects little and the ISIs approximate to a straight line. The delay rectification K current( ) caused by isn’t indispensable in the discharge’s formation process of the model. But ’s changing affects much in the discharge process of the neuron model. With ’s changing, the neuron model undergoes different dynamic bifurcation process, and has plenty of discharge patterns such as the chaos, period, and so on. This investigation is helpful to know and investigate the dynamic characteristics and the bifurcation mechanism of the hippocampal neuron; and it provides a certain theory assist to investigate the neural diseases such as the Alzheimer disease by neurodynamics. Na g