Prevalence of Vancomycin-resistant Enterococci Colonization, and Susceptibility to linezolid in Pediatric Intensive Care Units of a Referral Pediatric Center in Tehran, Iran
Author(s) -
Alireza Nateghian,
Seyed Mohammad Ghasemi Ahari,
Arash Lahouti Harahdashti,
M Navidnia,
Mitra Mehrazma
Publication year - 2014
Publication title -
archives of pediatric infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 12
eISSN - 2322-1836
pISSN - 2322-1828
DOI - 10.5812/pedinfect.16970
Subject(s) - medicine , linezolid , pediatric intensive care unit , antibiotics , pediatrics , colonization , clindamycin , intensive care unit , enterococcus , vancomycin , intensive care medicine , biology , bacteria , microbiology and biotechnology , genetics , staphylococcus aureus
Results: A total of 71 patients with a mean age of 29.1 ± 38.5 months were enrolled in this study. The prevalence of VRE rectal colonization was 66.2%. None of the potential risk factors including age, gender, comorbidities, previous admission into ICU, length of stay in ICU, presence of invasive devices were significantly associated with VRE colonization. Linezolid-susceptible isolated strains accounted 97.9%. Conclusions: The prevalence of VRE was higher compared to previous reports from local and international studies. In order to control the spread of VRE, appropriate use of antibiotics, adherence to infection control measures, and shortening the duration of ICU stay is highly recommended.
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