Staphylococcus aureus Enterotoxin B Down-Regulates the Expression of Transforming Growth Factor-Beta (TGF-β) Signaling Transducers in Human Glioblastoma | Zendy

Abolfazl Akbari | Zendy; Zohreh Farahnejad | Zendy; Javad Akhtari | Zendy; Mahdi Abastabar | Zendy; Gholam Reza Mobini | Zendy; Amir Seied Ali Mehbod | Zendy

Open Access

Staphylococcus aureus Enterotoxin B Down-Regulates the Expression of Transforming Growth Factor-Beta (TGF-β) Signaling Transducers in Human Glioblastoma

Author(s) -

Abolfazl Akbari,

Zohreh Farahnejad,

Javad Akhtari,

Mahdi Abastabar,

Gholam Reza Mobini,

Amir Seied Ali Mehbod

Publication year - 2016

Publication title -

jundishapur journal of microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.281

H-Index - 29

eISSN - 2008-4161

pISSN - 2008-3645

DOI - 10.5812/jjm.27297

Subject(s) - enterotoxin , transforming growth factor , real time polymerase chain reaction , transforming growth factor beta , cell growth , cancer research , signal transduction , messenger rna , gene expression , biology , microbiology and biotechnology , medicine , gene , genetics , escherichia coli

We suggested that SEB could represent an agent that can significantly decrease smad2/3 expression in glioblastoma cells, leading to moderate TGF-β growth signaling and the reduction of tumor cell proliferation.

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