Open AccessCorrelation Between Hypertension, C-Reactive Protein and Serum Uric Acid With Psychological Well-being
Author(s) -
Ali Maleki,
Saeid Samandari,
Osvaldo P. Almeida,
Scott Reza Jafarian Kerman,
Mahdi Abdolvand,
Farshid Aliyari,
Saeid Foroughi
Publication year - 2014
Publication title -
iranian red crescent medical journal
Language(s) - English
Resource type - Journals
eISSN - 2074-1812
pISSN - 2074-1804
DOI - 10.5812/ircmj.17205
Subject(s) - general health questionnaire , medicine , hyperuricemia , uric acid , mental health , distress , correlation , population , cross sectional study , psychiatry , clinical psychology , pathology , environmental health , geometry , mathematics
Background: Multiple population-based human studies have established a strong association between increasing levels of serum C-reactive protein, uric acid and subsequent development of hypertension. Objectives: We aimed to investigate the association between mental well-being with presence of hypertension, hyperuricemia and hs-CRP levels. Patients and Methods: This was a cross sectional study of 801 individuals aged 35-85 years old in Broujerd, Iran, included by randomized cluster sampling. General Health Questionnaire (GHQ-12) for assessing mental health/distress level, MONICA standard questions for evaluating hypertension history, serum hs-CRP and Serum Uric Acid (SUA) were evaluated Data were analyzed by appropriate statistical test such as chi-square, T-test and correlation. Results: One hundred eighty five patients (23.1%) had high distress/minor psychiatric disorders. SUA had significant association with hypertension (r = 0.64, P = 0.034). No significant relation was observed between hs-CRP and hypertension. The correlation between GHQ and hs-CRP was not significant but a weak and negative correlation was found between GHQ and SUA SUA (P = 0.012, r = -0.089). Conclusions: The weak and strong correlation among these parameters indicate that mental wellbeing relays on physical wellness and interact with each other; therefore, controlling hypertension along with uric acid control may effect mental health of any kind of patients.