Open AccessEvaluation of Oral Tiazinidine Effects on [intraoperative] Hemodynamic Responses During Direct Laryngoscopy Under General Anesthesia
Author(s) -
Masoomeh Tabari,
Mohammad Alipour,
Hamideh Esalati
Publication year - 2013
Publication title -
iranian red crescent medical journal
Language(s) - English
Resource type - Journals
eISSN - 2074-1812
pISSN - 2074-1804
DOI - 10.5812/ircmj.11540
Subject(s) - medicine , anesthesia , propofol , heart rate , blood pressure , shivering , intubation , tizanidine , laryngoscopy , tracheal intubation , hemodynamics , sevoflurane , premedication , mean arterial pressure , spasticity
Direct laryngoscopy and tracheal intubation can result in blood pressure and heart rate increase which in turn may lead to myocardial ischemia, cerebral hemorrhage, and even death in susceptible patients. Tizanidine is α2-receptor agonists that suppresses central sympathetic system.