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Body Composition Changes Associated With Methadone Treatment
Author(s) -
Gamal Sadek,
Simon Chiu,
Zack Z. Cernovsky
Publication year - 2016
Publication title -
international journal high risk behaviors and addiction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.266
H-Index - 13
ISSN - 2251-8711
DOI - 10.5812/ijhrba.27587
Subject(s) - bioelectrical impedance analysis , methadone , medicine , body mass index , basal metabolic rate , basal (medicine) , lean body mass , fat mass , composition (language) , opiate , anesthesia , physiology , endocrinology , body weight , diabetes mellitus , linguistics , philosophy , receptor
BackgroundMethadone is associated with a statistically significant increase in BMI in the first 2 years of treatment.ObjectivesTo evaluate the changes of body composition (bone mass, % fat, % muscle mass, % water, and basal metabolic rate) related to this increase.Patients and MethodsChanges in body composition were monitored, via bioelectrical impedance, in 29 patients in methadone treatment for opiate dependency (age 18 to 44, mean = 29.3, SD = 7.0, 13 men, 16 women).ResultsWithin one year from admission to treatment, a statistically significant (t-tests, P < 0.05) increase was noted in their body mass index (BMI), % of body fat, average body mass, and average basal metabolic rate, and relative decrease in their % of muscle mass and % of bone mass. Neither absolute bone mass nor muscle mass changed significantly.ConclusionsPhysicians involved in care of methadone patients should recommend dietary and lifestyle changes to improve their overall health

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