Effects of Dimethyl Phthalate (DMP) on Serum Sex Hormone Levels and Apoptosis in C57 Female Mice | Zendy

Yue Mei | Zendy; Ma Rongshuang | Zendy; Ruizhi Zhang | Zendy; Hongyuan Huang | Zendy; Tan Qiyue | Zendy; Zhao Shu-hua | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effects of Dimethyl Phthalate (DMP) on Serum Sex Hormone Levels and Apoptosis in C57 Female Mice

Author(s) -

Yue Mei,

Ma Rongshuang,

Ruizhi Zhang,

Hongyuan Huang,

Tan Qiyue,

Zhao Shu-hua

Publication year - 2019

Publication title -

international journal of endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.652

H-Index - 23

eISSN - 1726-9148

pISSN - 1726-913X

DOI - 10.5812/ijem.82882

Subject(s) - medicine , dimethyl phthalate , kowsar , apoptosis , hormone , sex hormone binding globulin , endocrinology , traditional medicine , phthalate , physiology , biology , chemistry , biochemistry , organic chemistry , androgen

Prolonged exposure to DMP led to decreased secretion of FSH hormones and increased secretion of E2 and LH hormones. Furthermore, DMP interfered with the pituitary-ovary axis and increased the apoptosis rate of ovarian granulosa cells. Therefore, prolonged exposure to DMP is likely to have negative effects on reproduction and development.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research