Growth Hormone Did Not Activate Its Intracellular Signaling Molecules in Rats’ Liver Hepatocytes During Early Life Period
Author(s) -
Ruonan Li,
Hong Pan,
Hainan Lan,
Xin Zheng
Publication year - 2018
Publication title -
international journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 23
eISSN - 1726-9148
pISSN - 1726-913X
DOI - 10.5812/ijem.61385
Subject(s) - stat5 , intracellular , stat3 , janus kinase 2 , janus kinase , endocrinology , medicine , growth hormone receptor , period (music) , kinase , extracellular , signal transduction , western blot , hormone , biology , growth hormone , microbiology and biotechnology , cytokine , receptor , biochemistry , physics , acoustics , gene
JAK2, STAT5, STAT3, STAT1, and ERK1/2 were not simultaneously activated by GH in newborn rats; this finding may be one of the underlying mechanism of GH insensitivity in newborn rats.
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