Effects of raloxifene on bone metabolism in hemodialysis patients with type 2 diabetes
Author(s) -
Osamu Saitô,
Takako Saitô,
Shinji Asakura,
Tetsu Akimoto,
Makoto Inoue,
Yukio Ando,
Shigeaki Muto,
Eiji Kusano
Publication year - 2012
Publication title -
international journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 23
eISSN - 1726-9148
pISSN - 1726-913X
DOI - 10.5812/ijem.3794
Subject(s) - medicine , raloxifene , bone remodeling , osteoporosis , endocrinology , hemodialysis , bone mineral , diabetes mellitus , renal osteodystrophy , kidney disease , cancer , estrogen receptor , breast cancer
Osteoporosis and chronic kidney disease are common conditions in older adults, and often occur concurrently. Bone disease is caused by increased bone turnover accompanying secondary hyperparathyroidism, and by factors such as bone metabolic disorder accompanying kidney disease and postmenopausal or age-related osteoporosis, even in hemodialysis patients. Raloxifene is commonly used for the treatment of postmenopausal osteoporosis in the general population, and may be a treatment option for osteoporosis in hemodialysis patients. However, the effects of raloxifene in hemodialysis patients with type 2 diabetes have not been examined in detail.
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