Pico-Tesla TMS Therapy on Multiple Sclerosis

BackgroundMagnetoencephalography (MEG) is a well-established noninvasive method for investigating human brain activity.ObjectivesThe present study aimed at identifying any change in the brain state after pico- Tesla Transcranial Magnetic Stimulation (pT-TMS) on patients with multiple sclerosis (MS).MethodsA whole-head 122 - channel MEG system in a magnetically shielded room with low magnetic noise was used. The study population comprised of 2 male and 8 female volunteers with MS, with a mean age of 41.3 ± 9.5 years. External magnetic field of pT-TMS was applied on the above patients with proper field characteristics (magnetic field amplitude: 1 - 7.5 pT, frequency: the alpha rhythm of the patient 8 - 13 Hz), obtained prior to the application of pT-TMS.ResultsA significant effect was observed with an increase of frequencies in the range of 2 - 7 Hz among the participants. The results were statistically significant in 7 out of 10 patients (70%).ConclusionsThe pT-TMS has the prospective to be a significant noninvasive secure and effective means in managing MS symptoms