Flow Cytometry of CD64, HLA-DR, CD25, and TLRs for Diagnosis and Prognosis of Sepsis in Critically Ill Patients Admitted to the Intensive Care Unit: A Review Article
Author(s) -
Hassan Soleimanpour,
Sarvin Sanaie,
Ali Akbar Movassaghpour,
Hadi Hamishehkar,
Ali Akbar Ghamari,
Seyed Pouya Paknezhad,
Ata Mahmoodpoor,
Kamran Shadvar
Publication year - 2018
Publication title -
anesthesiology and pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.438
H-Index - 26
eISSN - 2228-7531
pISSN - 2228-7523
DOI - 10.5812/aapm.83128
Subject(s) - medicine , sepsis , cd64 , intensive care medicine , flow cytometry , critically ill , immune system , intensive care unit , hla dr , immunology , antigen
Sepsis is an important health problem with a high burden on health systems. Finding new aspects of immune system function in sepsis showed a new role for flow cytometry in the diagnosis of sepsis. We made a review on the role of CD64, HLA-DR, CD25, and TLRs as more useful flow cytometric tools in diagnosing sepsis, both in adults, and neonates. According to our results, we concluded that for diagnosis and treatment of the septic, flow cytometry can play an important role so that it can be used as a novel method in individualized treatment of septic patients based on their immune system situation.
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