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Anesthetic Considerations for Angelman Syndrome: Case Series and Review of the Literature
Author(s) -
Mary E. Warner,
David P. Martin,
Mark A. Warner,
Ralitza H. Gavrilova,
Juraj Šprung,
Toby N. Weingarten
Publication year - 2017
Publication title -
anesthesiology and pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.438
H-Index - 26
eISSN - 2228-7531
pISSN - 2228-7523
DOI - 10.5812/aapm.57826
Subject(s) - medicine , angelman syndrome , anesthetic , anesthesia , intensive care medicine , biochemistry , chemistry , gene
Angelman syndrome patients often require anesthesia for relatively innocuous procedures, and their speech impairment and happy demeanor can confound postoperative pain assessment. Patients can have atypical responses to benzodiazepines. Craniofacial abnormalities can complicate airway management. Although not encountered in this series, anesthesiologists need to be aware that Angelman syndrome patients have developed malignant bradydysrhythmias while anesthetized.

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