Fabrications, Applications and Challenges of Solid-State Nanopores: A Mini Review | Zendy

Zifan Tang | Zendy; Daihua Zhang | Zendy; Weiwei Cui | Zendy; Hao Zhang | Zendy; Wei Pang | Zendy; Xuexin Duan | Zendy

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Fabrications, Applications and Challenges of Solid-State Nanopores: A Mini Review

Author(s) -

Zifan Tang,

Daihua Zhang,

Weiwei Cui,

Hao Zhang,

Wei Pang,

Xuexin Duan

Publication year - 2016

Publication title -

nanomaterials and nanotechnology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.412

H-Index - 21

ISSN - 1847-9804

DOI - 10.5772/64015

Subject(s) - nanopore , solid state , nanopore sequencing , nanotechnology , materials science , fabrication , compatibility (geochemistry) , dna sequencing , dna , engineering physics , engineering , chemistry , medicine , biochemistry , alternative medicine , pathology , composite material

Nanopore sensors are expected to be one of the most promising next generation sequencing technologies, with label-free, amplification-free and high-throughput fea‐ tures, as well as rapid detections and low cost. Solid-state nanopores have been widely explored due to their diverse fabrication methods and CMOS compatibility. Here, we highlight the fabrication methods of solid-state nanopores, including the direct opening and the tuning methods. In addition, molecular translocation developments, DNA sequencing and protein detections are summarized. Finally, the latest progress relating to solid-state nanopores is discussed, which helps to offer a comprehensive under‐ standing of the current situation for solid-state nanopore sensors

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