Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum Indicum Fruits | Zendy

Punuri Jayasekhar Babu | Zendy; Pragya Sharma | Zendy; S. Saranya | Zendy; Ranjan Tamuli | Zendy; Utpal Bora | Zendy

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Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum Indicum Fruits

Author(s) -

Punuri Jayasekhar Babu,

Pragya Sharma,

S. Saranya,

Ranjan Tamuli,

Utpal Bora

Publication year - 2013

Publication title -

nanomaterials and nanotechnology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.412

H-Index - 21

ISSN - 1847-9804

DOI - 10.5772/56608

Subject(s) - colloidal gold , fourier transform infrared spectroscopy , biomolecule , materials science , nanoparticle , transmission electron microscopy , nuclear chemistry , spectroscopy , adsorption , infrared spectroscopy , energy dispersive x ray spectroscopy , biocompatibility , chemical engineering , nanotechnology , scanning electron microscope , organic chemistry , chemistry , physics , quantum mechanics , engineering , metallurgy , composite material

This paper reports on the eco‐friendly synthesisof gold nanoparticles (AuNPs) using Solanum indicumfruit extract (SFE). We have evaluated various parametersfor synthesis of AuNPs such as SFE (0.03%), HAuCl4 (0.5mM) and reaction time (20 seconds). The synthesizedAuNPs were characterized with different physicaltechniques such as transmission electron microscopy(TEM), Fourier transform infrared (FT‐IR) spectroscopy,X‐ray diffraction (XRD) and energy dispersive X‐rayspectroscopy (EDX). TEM experiments showed thatAuNPs presented an anisotropic shape and size rangingfrom 5‐50nm. FT‐IR spectroscopy revealed thatbiomolecules containing an amine group (–NH2), acarbonyl group, –OH groups and other stabilizingfunctional groups were adsorbed on the surface of thesynthesized AuNPs. EDX showed the presence of theelements on the surface of the AuNPs. The cytotoxicity ofthe synthesized AuNPs were tested on two differenthuman cancer cell lines, HeLa and MCF‐7 and werefound to be nontoxic, thus providing an opportunity to beused in biomedical applications

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