A Study on the Effect of Gallotannin Treatment of Ceramide-containing Fibers on Atopic Skin Diseases | Zendy

Taekyeong Kim | Zendy; Nayoung Cho | Zendy; Heejung Ma | Zendy; Gwang Wung Yang | Zendy; Yong Hwan Rho | Zendy

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A Study on the Effect of Gallotannin Treatment of Ceramide-containing Fibers on Atopic Skin Diseases

Author(s) -

Taekyeong Kim,

Nayoung Cho,

Heejung Ma,

Gwang Wung Yang,

Yong Hwan Rho

Publication year - 2013

Publication title -

textile coloration and finishing

Language(s) - English

Resource type - Journals

eISSN - 2234-036X

pISSN - 1229-0033

DOI - 10.5764/tcf.2013.25.4.271

Subject(s) - ceramide , transepidermal water loss , atopic dermatitis , enzyme , dermatology , medicine , chemistry , biochemistry , stratum corneum , pathology , apoptosis

In order to investigate the effect of gallotannin treatment to ceramide-containing fabrics on atopic skin diseases, the agglomeration of standard protein BSA and the deactivation of model enzyme were examined. The gallotannin treated on ceramide-containing fabrics precipitated the standard protein, BSA, and therefore deactivated the model enzyme by 70% at 6% treatment concentration. Wash durability should be improved after around 5 cycles of washing. Clinical test of the gallotannin-treated fabrics was carried out on mice for two test items, transepidermal water loss assay and severity score of diseased skin of mice. The results showed significant level of improvement of atopic skin diseases compared with the negative controled.

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