Second report of a Nocardia beijingensis infection in the United States: nodular scleritis with in vitro imipenem resistance | Zendy

Andrés González | Zendy; Eric Jennings | Zendy; Sasha Vaziri | Zendy; Anthony T. Yachnis | Zendy; Anup Kubal | Zendy

Open Access

Second report of a Nocardia beijingensis infection in the United States: nodular scleritis with in vitro imipenem resistance

Author(s) -

Andrés González,

Eric Jennings,

Sasha Vaziri,

Anthony T. Yachnis,

Anup Kubal

Publication year - 2016

Publication title -

digital journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.223

H-Index - 7

ISSN - 1542-8958

DOI - 10.5693/djo.02.2016.01.003

Subject(s) - nocardia , scleritis , medicine , imipenem , pathology , gram staining , antibiotics , nodule (geology) , microbiology and biotechnology , bacteria , antibiotic resistance , biology , ophthalmology , genetics , uveitis , paleontology

We describe the case of a 52-year-old woman with scleritis caused by an imipenem-resistant strain of Nocardia beijingensis . The patient presented with pain, redness, and nodules on the sclera of 8 weeks' duration. A Gram stain from a nodule on the superonasal aspect of the globe was initially negative. After empiric treatment for an autoimmune etiology, cytopathology confirmed filamentous bacteria. A presumptive diagnosis of Nocardia scleritis was made, and medical management was based on a literature review on treatments for Nocardia infections. Cultures returned confirming Nocardia beijingensis . Antibiotic sensitivity testing confirmed the correct initial management. The patient's scleritis resolved with a good visual outcome.

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