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Povidone-iodine concentration and in vitro killing time of bacterial corneal ulcer isolates
Author(s) -
Jagger C. Koerner,
Mary J. George,
Elizabeth A. Kissam,
Michael G. Rosco
Publication year - 2018
Publication title -
digital journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.223
H-Index - 7
ISSN - 1542-8958
DOI - 10.5693/djo.01.2018.06.001
Subject(s) - serial dilution , in vitro , microbiology and biotechnology , agar , staphylococcus aureus , bacteria , agar plate , iodine , biology , chemistry , medicine , pathology , biochemistry , genetics , alternative medicine , organic chemistry
The concentration and dosing of povidone-iodine (PI) solution used in surgical site prophylaxis are variable. Prior in vitro work has demonstrated that dilute PI solutions (<1%) had greater bactericidal activity than stock solutions (10%). Studies using pathologic clinical isolates from the eye have yielded mixed results. The purpose of the current study was to evaluate the efficacy of different concentrations of PI on pathologic ocular surface isolates.

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