Induction of Apoptosis and Cytotoxic Activities of Iranian Orthodox Black Tea Extract (BTE) Using in vitro Models. | Zendy

Amirala Aghbali | Zendy; Moradi Abbasabadi F | Zendy; Abbas Delazar | Zendy; Vosough Hosseini S | Zendy; Zare Shahneh F | Zendy; Behzad Baradaran | Zendy; Maryam Janani | Zendy

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Induction of Apoptosis and Cytotoxic Activities of Iranian Orthodox Black Tea Extract (BTE) Using in vitro Models.

Author(s) -

Amirala Aghbali,

Moradi Abbasabadi F,

Abbas Delazar,

Vosough Hosseini S,

Zare Shahneh F,

Behzad Baradaran,

Maryam Janani

Publication year - 2014

Publication title -

doaj (doaj: directory of open access journals)

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.773

H-Index - 35

ISSN - 2228-5881

DOI - 10.5681/apb.2014.037

Subject(s) - dna fragmentation , apoptosis , trypan blue , cytotoxic t cell , fragmentation (computing) , tunel assay , programmed cell death , chemistry , mtt assay , cytotoxicity , traditional medicine , microbiology and biotechnology , biology , in vitro , biochemistry , medicine , ecology

Plant-derivate therapeutic agents can perform cancer chemotherapeutic activity through triggering apoptotic cell death. Our aim was to investigate the cytotoxic effects, induction of apoptosis, and the mechanism of cell death of Iranian orthodox black tea extracts (BTEs) and hydro methanolic purified fractions (40, 60, 80 and 100%) in KB cells (oral squamous cell carcinoma).

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