The effect of chronic administration of buspirone on 6-hydroxydopamine-induced catalepsy in rats. | Zendy

Hamid Sharifi | Zendy; Alireza Mohajjel Nayebi | Zendy; Safar Farajnia | Zendy

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The effect of chronic administration of buspirone on 6-hydroxydopamine-induced catalepsy in rats.

Author(s) -

Hamid Sharifi,

Alireza Mohajjel Nayebi,

Safar Farajnia

Publication year - 2012

Publication title -

pubmed

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.773

H-Index - 35

ISSN - 2228-5881

DOI - 10.5681/apb.2012.019

Subject(s) - catalepsy , buspirone , serotonergic , pharmacology , medicine , hydroxydopamine , haloperidol , dopaminergic , dopamine , serotonin , receptor

Several evidences show that serotonergic neurons play a role in the regulation of movements executed by the basal ganglia. Recently we have reported that single dose of buspirone improved 6-hydroxydopamine (6-OHDA) and haloperidol-induced catalepsy. This study is aimed to investigate effect of chronic intraperitoneal (i.p.) administration of buspirone on 6-OHDA-induced catalepsy in male Wistar rats.

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