Sleep Homeostatic and Waking Behavioral Phenotypes inEgr3-Deficient Mice Associated with Serotonin Receptor 5-HT2 Deficits
Author(s) -
Janne Grønli,
William C. Clegern,
Michelle Schmidt,
Rahmi S. Nemri,
Michael J. Rempe,
Amelia L. Gallitano,
Jonathan P. Wisor
Publication year - 2016
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.6324
Subject(s) - serotonin , sleep (system call) , phenotype , neuroscience , psychology , receptor , serotonin uptake inhibitors , wakefulness , homeostasis , medicine , endocrinology , biology , electroencephalography , genetics , fluoxetine , computer science , gene , operating system
The expression of the immediate early gene early growth response 3 ( Egr3 ) is a functional marker of brain activity including responses to novelty, sustained wakefulness, and sleep. We examined the role of this gene in regulating wakefulness and sleep.
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