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Intermittent Short Sleep Results in Lasting Sleep Wake Disturbances and Degeneration of Locus Coeruleus and Orexinergic Neurons
Author(s) -
Yan Zhu,
Polina Fenik,
Guanxia Zhan,
Rebecca T. Somach,
Ryan Xin,
Sigrid C. Veasey
Publication year - 2016
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.6030
Subject(s) - locus coeruleus , wakefulness , sleep onset , circadian rhythm , sleep (system call) , neuron , neuroscience , psychology , endocrinology , medicine , electroencephalography , central nervous system , insomnia , psychiatry , computer science , operating system
Intermittent short sleep (ISS) is pervasive among students and workers in modern societies, yet the lasting consequences of repeated short sleep on behavior and brain health are largely unexplored. Wake-activated neurons may be at increased risk of metabolic injury across sustained wakefulness.

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