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Effect of Oral JZP-110 (ADX-N05) on Wakefulness and Sleepiness in Adults with Narcolepsy: A Phase 2b Study
Author(s) -
Chad Ruoff,
Todd J. Swick,
Robert C. Doekel,
Hélène A. Emsellem,
Neil T. Feldman,
Russell Rosenberg,
Gary Bream,
Moise Khayrallah,
Yuan Lü,
Jed Black
Publication year - 2016
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.5968
Subject(s) - narcolepsy , wakefulness , modafinil , multiple sleep latency test , medicine , anesthesia , psychology , cataplexy , audiology , excessive daytime sleepiness , psychiatry , insomnia , sleep disorder , electroencephalography
To evaluate the efficacy and safety of oral JZP-110, a second-generation wake-promoting agent with dopaminergic and noradrenergic activity, for treatment of impaired wakefulness and excessive sleepiness in adults with narcolepsy.

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