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Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects
Author(s) -
Ricardo S. Osorio,
Emma L. Ducca,
Margaret Wohlleber,
Emily Tanzi,
Tyler Gumb,
Akosua Twumasi,
Samuel Tweardy,
Clifton Lewis,
Esther Fischer,
Viachaslau Koushyk,
Maria Cuartero-Toledo,
Mohammed O. Sheikh,
Elizabeth Pirraglia,
Henrik Zetterberg,
Kaj Blennow,
ShouEn Lu,
Lisa Mosconi,
Lidia Glodzik,
Sonja Schuetz,
Andrew W. Varga,
Indu Ayappa,
David M. Rapoport,
Mony J. de Leon
Publication year - 2016
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.5846
Subject(s) - orexin , medicine , cerebrospinal fluid , sleep apnea , confounding , endocrinology , psychology , oncology , receptor , neuropeptide
To evaluate the role of orexin-A with respect to cerebrospinal fluid (CSF) Alzheimer disease (AD) biomarkers, and explore its relationship to cognition and sleep characteristics in a group of cognitively normal elderly individuals.

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