An Examination of Methodological Paradigms for Calculating Upper Airway Critical Pressures during Sleep | Zendy

Grace W. Pien | Zendy; Brendan T Keenan | Zendy; Carole L. Marcus | Zendy; Bethany Staley | Zendy; Sarah J. Ratcliffe | Zendy; Nicholas Jackson | Zendy; William Wieland | Zendy; Yi Sun | Zendy; Richard J. Schwab | Zendy

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An Examination of Methodological Paradigms for Calculating Upper Airway Critical Pressures during Sleep

Author(s) -

Grace W. Pien,

Brendan T Keenan,

Carole L. Marcus,

Bethany Staley,

Sarah J. Ratcliffe,

Nicholas Jackson,

William Wieland,

Yi Sun,

Richard J. Schwab

Publication year - 2016

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.5736

Subject(s) - obstructive sleep apnea , critical closing pressure , closing (real estate) , airway , mathematics , medicine , anesthesia , hemodynamics , political science , law

The goal of this study was to examine different paradigms for determining critical closing pressures (Pcrit). Methods of determining Pcrit were compared, including direct observation of occluded (no flow) breaths versus inferring Pcrit from extrapolated data, and Pcrit generated by aggregating pressure-flow data from multiple runs versus Pcrit averaged across individual pressure-flow runs. The relationship between Pcrit and obstructive sleep apnea (OSA) was examined.

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