Neural Reward Processing Mediates the Relationship between Insomnia Symptoms and Depression in Adolescence | Zendy

Melynda D. Casement | Zendy; Kate Keenan | Zendy; Alison E. Hipwell | Zendy; Amanda E. Guyer | Zendy; Erika E. Forbes | Zendy

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Neural Reward Processing Mediates the Relationship between Insomnia Symptoms and Depression in Adolescence

Author(s) -

Melynda D. Casement,

Kate Keenan,

Alison E. Hipwell,

Amanda E. Guyer,

Erika E. Forbes

Publication year - 2016

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.5460

Subject(s) - anticipation (artificial intelligence) , psychology , depression (economics) , prefrontal cortex , longitudinal study , insomnia , major depressive disorder , anterior cingulate cortex , clinical psychology , psychiatry , medicine , cognition , pathology , artificial intelligence , computer science , economics , macroeconomics

Emerging evidence suggests that insomnia may disrupt reward-related brain function-a potentially important factor in the development of depressive disorder. Adolescence may be a period during which such disruption is especially problematic given the rise in the incidence of insomnia and ongoing development of neural systems that support reward processing. The present study uses longitudinal data to test the hypothesis that disruption of neural reward processing is a mechanism by which insomnia symptoms-including nocturnal insomnia symptoms (NIS) and nonrestorative sleep (NRS)-contribute to depressive symptoms in adolescent girls.

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