Cerebral Blood Flow Response to Hypercapnia in Children with Obstructive Sleep Apnea Syndrome | Zendy

David R. Busch | Zendy; Jennifer M. Lynch | Zendy; Madeline Winters | Zendy; Ann L. McCarthy | Zendy; John J. Newland | Zendy; Tiffany S. Ko | Zendy; Mary Anne Cornaglia | Zendy; Jerilynn Radcliffe | Zendy; Joseph M. McDonough | Zendy; John Samuel | Zendy; Edward Matthews | Zendy; Rui Xiao | Zendy; Arjun G. Yodh | Zendy; Carole L. Marcus | Zendy; Daniel J. Licht | Zendy; Ignacio E. Tapia | Zendy

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Cerebral Blood Flow Response to Hypercapnia in Children with Obstructive Sleep Apnea Syndrome

Author(s) -

David R. Busch,

Jennifer M. Lynch,

Madeline Winters,

Ann L. McCarthy,

John J. Newland,

Tiffany S. Ko,

Mary Anne Cornaglia,

Jerilynn Radcliffe,

Joseph M. McDonough,

John Samuel,

Edward Matthews,

Rui Xiao,

Arjun G. Yodh,

Carole L. Marcus,

Daniel J. Licht,

Ignacio E. Tapia

Publication year - 2015

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.5350

Subject(s) - hypercapnia , medicine , obstructive sleep apnea , cerebral blood flow , anesthesia , wakefulness , interquartile range , apnea , acidosis , electroencephalography , psychiatry

Children with obstructive sleep apnea syndrome (OSAS) often experience periods of hypercapnia during sleep, a potent stimulator of cerebral blood flow (CBF). Considering this hypercapnia exposure during sleep, it is possible that children with OSAS have abnormal CBF responses to hypercapnia even during wakefulness. Therefore, we hypothesized that children with OSAS have blunted CBF response to hypercapnia during wakefulness, compared to snorers and controls.

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