Cortical Drive to Breathe during Wakefulness in Patients with Obstructive Sleep Apnea Syndrome | Zendy

Claire Launois | Zendy; Valérie Attali | Zendy; Marjolaine Georges | Zendy; Mathieu Raux | Zendy; Élise Morawiec | Zendy; Isabelle Rivals | Zendy; Isabelle Arnulf | Zendy; Thomas Similowski | Zendy

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Cortical Drive to Breathe during Wakefulness in Patients with Obstructive Sleep Apnea Syndrome

Author(s) -

Claire Launois,

Valérie Attali,

Marjolaine Georges,

Mathieu Raux,

Élise Morawiec,

Isabelle Rivals,

Isabelle Arnulf,

Thomas Similowski

Publication year - 2015

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.5156

Subject(s) - wakefulness , obstructive sleep apnea , medicine , arousal , apnea , polysomnography , anesthesia , airway , cardiology , electroencephalography , psychology , neuroscience , psychiatry

The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity. The objective of this study was to test whether awake OSAS patients would exhibit a similar cortical activity.

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