Associations of Sleep Apnea,NRG1Polymorphisms, Alcohol Consumption, and Cerebral White Matter Hyperintensities: Analysis with Genome-Wide Association Data | Zendy

Inkyung Baik | Zendy; Hyung Suk Seo | Zendy; Daewui Yoon | Zendy; Seong Hwan Kim | Zendy; Chol Shin | Zendy

Open Access

Associations of Sleep Apnea,NRG1Polymorphisms, Alcohol Consumption, and Cerebral White Matter Hyperintensities: Analysis with Genome-Wide Association Data

Author(s) -

Inkyung Baik,

Hyung Suk Seo,

Daewui Yoon,

Seong Hwan Kim,

Chol Shin

Publication year - 2015

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.4830

Subject(s) - genome wide association study , odds ratio , medicine , body mass index , sleep apnea , obstructive sleep apnea , obesity , genetics , single nucleotide polymorphism , biology , genotype , gene

There are few studies on gene-environment interactions with obstructive sleep apnea (OSA). Our study aimed to explore genetic polymorphisms associated with OSA using genome-wide association (GWA) data and evaluate the effects of relevant polymorphisms on the association between risk factors, including obesity and alcohol consumption, and OSA. We also investigated on these associations in relation to cerebral white matter hyperintensities (WMH) on magnetic resonance images.

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