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The Use of Benzodiazepine Receptor Agonists and Risk of Respiratory Failure in Patients with Chronic Obstructive Pulmonary Disease: A Nationwide Population-Based Case-Control Study
Author(s) -
Su-Jung Chen,
Chiu-Mei Yeh,
TzeFan Chao,
ChiaJen Liu,
Kang-Ling Wang,
TzengJi Chen,
Pesus Chou,
FuDer Wang
Publication year - 2015
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.4808
Subject(s) - medicine , copd , odds ratio , benzodiazepine , case control study , confidence interval , population , risk factor , respiratory failure , environmental health , receptor
Insomnia is prevalent in patients with chronic obstructive pulmonary disease (COPD), and benzodiazepine receptor agonists (BZRAs) are the most commonly used drugs despite their adverse effects on respiratory function. The aim of this study was to investigate whether the use of BZRAs was associated with an increased risk of respiratory failure (RF) in COPD patients.

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