Neural Respiratory Drive and Arousal in Patients with Obstructive Sleep Apnea Hypopnea | Zendy

Sichang Xiao | Zendy; Baiting He | Zendy; Joerg Steier | Zendy; John Moxham | Zendy; Michael I. Polkey | Zendy; Yuanming Luo | Zendy

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Neural Respiratory Drive and Arousal in Patients with Obstructive Sleep Apnea Hypopnea

Author(s) -

Sichang Xiao,

Baiting He,

Joerg Steier,

John Moxham,

Michael I. Polkey,

Yuanming Luo

Publication year - 2015

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.4746

Subject(s) - hypopnea , obstructive sleep apnea , apnea , polysomnography , medicine , anesthesia , arousal , sleep apnea , cardiology , psychology , neuroscience

It has been hypothesized that arousals after apnea and hypopnea events in patients with obstructive sleep apnea are triggered when neural respiratory drive exceeds a certain level, but this hypothesis is based on esophageal pressure data, which are dependent on flow and lung volume. We aimed to determine whether a fixed threshold of respiratory drive is responsible for arousal at the termination of apnea and hypopnea using a flow independent technique (esophageal diaphragm electromyography, EMGdi) in patients with obstructive sleep apnea.

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