Open AccessA New Model to Study Sleep Deprivation-Induced Seizure
Author(s) -
Brendan P. Lucey,
Averi Leahy,
Regine Rosas,
Paul J. Shaw
Publication year - 2015
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.4674
Subject(s) - sleep deprivation , sleep (system call) , epilepsy , psychology , medicine , anesthesia , audiology , neuroscience , circadian rhythm , computer science , operating system
A relationship between sleep and seizures is well-described in both humans and rodent animal models; however, the mechanism underlying this relationship is unknown. Using Drosophila melanogaster mutants with seizure phenotypes, we demonstrate that seizure activity can be modified by sleep deprivation.
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