Sleep Deprivation and Divergent Toll-like Receptor-4 Activation of Cellular Inflammation in Aging | Zendy

Judith Carroll | Zendy; Carmen Carrillo | Zendy; Richard G. Olmstead | Zendy; Tuff Witarama | Zendy; Elizabeth C. Breen | Zendy; Megumi Yokomizo | Zendy; Teresa E. Seeman | Zendy; Michael R. Irwin | Zendy

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Sleep Deprivation and Divergent Toll-like Receptor-4 Activation of Cellular Inflammation in Aging

Author(s) -

Judith Carroll,

Carmen Carrillo,

Richard G. Olmstead,

Tuff Witarama,

Elizabeth C. Breen,

Megumi Yokomizo,

Teresa E. Seeman,

Michael R. Irwin

Publication year - 2015

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.4398

Subject(s) - sleep deprivation , inflammation , sleep (system call) , medicine , cytokine , sleep disorder , tumor necrosis factor alpha , interleukin 6 , sleep restriction , endocrinology , immunology , circadian rhythm , insomnia , psychiatry , computer science , operating system

Sleep disturbance and aging are associated with increases in inflammation, as well as increased risk of infectious disease. However, there is limited understanding of the role of sleep loss on age-related differences in immune responses. This study examines the effects of sleep deprivation on toll-like receptor activation of monocytic inflammation in younger compared to older adults.

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