Alteredin vitroEndothelial Repair and Monocyte Migration in Obstructive Sleep Apnea: Implication of VEGF and CRP | Zendy

Anne BriançonMarjollet | Zendy; Marion Henri | Zendy; JeanLouis Pépin | Zendy; Emeline Lemarié | Zendy; Patrick Lévy | Zendy; Renaud Tamisier | Zendy

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Alteredin vitroEndothelial Repair and Monocyte Migration in Obstructive Sleep Apnea: Implication of VEGF and CRP

Author(s) -

Anne BriançonMarjollet,

Marion Henri,

JeanLouis Pépin,

Emeline Lemarié,

Patrick Lévy,

Renaud Tamisier

Publication year - 2014

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.4180

Subject(s) - medicine , obstructive sleep apnea , monocyte , wound healing , inflammation , endocrinology , vascular endothelial growth factor , endothelial dysfunction , hypoxia (environmental) , immunology , chemistry , vegf receptors , organic chemistry , oxygen

Although obstructive sleep apnea (OSA) causes cardiovascular morbidities through atherosclerosis induced by inflammation and endothelial dysfunction, OSA patients exhibit elevated plasma vascular endothelial growth factor (VEGF), which may represent an adaptive response to intermittent hypoxia. The aims of this study were to investigate whether in vitro endothelial wound healing and monocyte migration are affected by patient serum, and to determine the implication of circulating factors (VEGF and C-reactive protein).

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