Chronic Sleep Fragmentation Induces Endothelial Dysfunction and Structural Vascular Changes in Mice | Zendy

Alba Carreras | Zendy; Shelley X. Zhang | Zendy; Eduard Peris | Zendy; Zhuanhong Qiao | Zendy; Alex GilelesHillel | Zendy; Richard Li | Zendy; Yang Wang | Zendy; David Gozal | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Chronic Sleep Fragmentation Induces Endothelial Dysfunction and Structural Vascular Changes in Mice

Author(s) -

Alba Carreras,

Shelley X. Zhang,

Eduard Peris,

Zhuanhong Qiao,

Alex GilelesHillel,

Richard Li,

Yang Wang,

David Gozal

Publication year - 2014

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.4178

Subject(s) - medicine , senescence , endothelial dysfunction , endocrinology , obstructive sleep apnea , blood pressure , pathology , cardiology

Sleep fragmentation (SF) is a common occurrence and constitutes a major characteristic of obstructive sleep apnea (OSA). SF has been implicated in multiple OSA-related morbidities, but it is unclear whether SF underlies any of the cardiovascular morbidities of OSA. We hypothesized that long-term SF exposures may lead to endothelial dysfunction and altered vessel wall structure.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research