Male Fertility Is Reduced by Chronic Intermittent Hypoxia Mimicking Sleep Apnea in Mice
Author(s) -
Marta Torres,
Ricardo LagunaBarraza,
Mireia Dalmases,
Alexandra Calle,
Eva Pericuesta,
Josep M. Montserrat,
Daniel Navajas,
Alfonso GutiérrezAdán,
Ramón Farré
Publication year - 2014
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.4166
Subject(s) - intermittent hypoxia , hypoxia (environmental) , endocrinology , oxidative stress , medicine , sperm , sperm motility , obstructive sleep apnea , gpx1 , semen analysis , andrology , semen , biology , glutathione peroxidase , superoxide dismutase , chemistry , infertility , pregnancy , oxygen , genetics , organic chemistry
Obstructive sleep apnea (OSA) is characterized by intermittent hypoxia and oxidative stress. However, it is unknown whether intermittent hypoxia mimicking OSA modifies male fertility. We tested the hypothesis that male fertility is reduced by chronic intermittent hypoxia mimicking OSA in a mouse model.
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