Hippocampal Substructural Vulnerability to Sleep Disturbance and Cognitive Impairment in Patients with Chronic Primary Insomnia: Magnetic Resonance Imaging Morphometry
Author(s) -
Eun Yeon Joo,
Hosung Kim,
Sooyeon Suh,
Seung Bong Hong
Publication year - 2014
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.3836
Subject(s) - atrophy , hippocampal formation , psychology , hippocampus , primary insomnia , pittsburgh sleep quality index , dentate gyrus , medicine , polysomnography , sleep disorder , audiology , magnetic resonance imaging , neuroscience , cognition , radiology , sleep quality , electroencephalography
Despite compelling evidence from animal studies indicating hippocampal subfield-specific vulnerability to poor sleep quality and related cognitive impairment, there have been no human magnetic resonance imaging (MRI) studies investigating the relationship between hippocampal subfield volume and sleep disturbance. Our aim was to investigate the pattern of volume changes across hippocampal subfields in patients with primary insomnia relative to controls.
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