Challenges in Diagnosing Narcolepsy without Cataplexy: A Consensus Statement
Author(s) -
Christian R. Baumann,
Emmanuel Mignot,
Gert Jan Lammers,
Sebastiaan Overeem,
Isabelle Arnulf,
David B. Rye,
Yves Dauvilliers,
Makoto Honda,
Judith Owens,
Giuseppe Plazzi,
Thomas E. Scammell
Publication year - 2014
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.3756
Subject(s) - narcolepsy , cataplexy , polysomnography , sleep paralysis , multiple sleep latency test , sleep disorder , actigraphy , psychology , modafinil , medicine , excessive daytime sleepiness , psychiatry , insomnia , electroencephalography
Diagnosing narcolepsy without cataplexy is often a challenge as the symptoms are nonspecific, current diagnostic tests are limited, and there are no useful biomarkers. In this report, we review the clinical and physiological aspects of narcolepsy without cataplexy, the limitations of available diagnostic procedures, and the differential diagnoses, and we propose an approach for more accurate diagnosis of narcolepsy without cataplexy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom