Insular Cortex Metabolite Changes in Obstructive Sleep Apnea
Author(s) -
Santosh K. Yadav,
Rajesh Kumar,
Paul M. Macey,
Mary A. Woo,
Frisca L. YanGo,
Ronald M. Harper
Publication year - 2014
Publication title -
sleep
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.3668
Subject(s) - insular cortex , obstructive sleep apnea , creatine , medicine , epworth sleepiness scale , pittsburgh sleep quality index , polysomnography , endocrinology , apnea , psychiatry , cognition , sleep quality
Adults with obstructive sleep apnea (OSA) show significant autonomic and neuropsychologic deficits, which may derive from damage to insular regions that serve those functions. The aim was to assess glial and neuronal status from anterior insular metabolites in OSA versus controls, using proton magnetic resonance spectroscopy (PMRS), and thus to provide insights for neuroprotection against tissue changes, and to reduce injury consequences.
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