Glucose and Fat Metabolism in Narcolepsy and the Effect of Sodium Oxybate: A Hyperinsulinemic-Euglycemic Clamp Study | Zendy

Claire E. H. M. Donjacour | Zendy; N. Ahmad Aziz | Zendy; Sebastiaan Overeem | Zendy; Andries Kalsbeek | Zendy; Hanno Pijl | Zendy; Gert Jan Lammers | Zendy

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Glucose and Fat Metabolism in Narcolepsy and the Effect of Sodium Oxybate: A Hyperinsulinemic-Euglycemic Clamp Study

Author(s) -

Claire E. H. M. Donjacour,

N. Ahmad Aziz,

Sebastiaan Overeem,

Andries Kalsbeek,

Hanno Pijl,

Gert Jan Lammers

Publication year - 2014

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.3592

Subject(s) - narcolepsy , lipolysis , medicine , endocrinology , cataplexy , insulin , insulin resistance , adipose tissue , neurology , psychiatry

Narcolepsy is associated with obesity though it is uncertain whether this is caused by changes in glucose and fat metabolism. Therefore, we performed a detailed analysis of systemic energy homeostasis in narcolepsy patients, and additionally, investigated whether it was affected by three months of sodium oxybate (SXB) treatment.

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