Increased Use-Dependent Plasticity in Chronic Insomnia
Author(s) -
Rachel E. Salas,
Joseph M. Galea,
Alyssa Gamaldo,
Charlene E. Gamaldo,
Richard P. Allen,
Michael T. Smith,
Gabriela Cantarero,
Barbara D. Lam,
Pablo Celnik
Publication year - 2014
Publication title -
sleep
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.3492
Subject(s) - neuroplasticity , neuroscience , transcranial magnetic stimulation , glutamatergic , psychology , insomnia , chronic pain , physical medicine and rehabilitation , medicine , context (archaeology) , gabaergic , chronic insomnia , cognition , stimulation , inhibitory postsynaptic potential , sleep disorder , psychiatry , glutamate receptor , biology , paleontology , receptor
During normal sleep several neuroplasticity changes occur, some of which are considered to be fundamental to strengthen memories. Given the evidence linking sleep to neuroplasticity, it is conceivable that individuals with chronic sleep disruption, such as patients with chronic insomnia (CI), would experience abnormalities in neuroplastic processes during daytime. Protocols testing use-dependent plasticity (UDP), one of the mechanisms underlying formation of motor memories traces, provide a sensitive measure to assess neuroplasticity in the context of motor training.
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