Low Morning Serum Cortisol Levels in Children with Tonsillar Hypertrophy and Moderate-to-Severe OSA
Author(s) -
Georgia Malakasioti,
Emmanouel Ι. Alexopoulos,
Vasiliki Varlami,
Konstantinos Chaidas,
Nikolaos Liakos,
Konstantinos I. Gourgoulianis,
Athanasios G. Kaditis
Publication year - 2013
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.2962
Subject(s) - medicine , morning , obstructive sleep apnea , polysomnography , endocrinology , muscle hypertrophy , tonsillectomy , glucocorticoid , obesity , tonsil , hypopnea , apnea–hypopnea index , apnea , anesthesia , surgery
Hypertrophic tonsillar tissue in children with obstructive sleep apnea (OSA) has enhanced expression of glucocorticoid receptors, which may reflect low endogenous cortisol levels. We have evaluated the effect of the interaction between tonsillar hypertrophy and OSA severity on morning serum cortisol levels.
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