Slow Wave Sleep Induced by GABA Agonist Tiagabine Fails to Benefit Memory Consolidation
Author(s) -
Gordon B. Feld,
Ines Wilhelm,
Ying Ma,
Sabine Groch,
Ferdinand Binkofski,
Matthias Mölle,
Jan Born
Publication year - 2013
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.2954
Subject(s) - tiagabine , memory consolidation , sleep (system call) , psychology , agonist , neuroscience , slow wave sleep , medicine , epilepsy , anesthesia , psychiatry , anticonvulsant , electroencephalography , hippocampus , computer science , operating system , receptor
Slow wave sleep (SWS) plays a pivotal role in consolidating memories. Tiagabine has been shown to increase SWS in favor of REM sleep without impacting subjective sleep. However, it is unknown whether this effect is paralleled by an improved sleep-dependent consolidation of memory.
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