Extended Remediation of Sleep Deprived-Induced Working Memory Deficits Using fMRI-guided Transcranial Magnetic Stimulation
Author(s) -
Bruce Luber,
Jason Steffener,
Adrienne M. Tucker,
Christian Habeck,
Angel V. Peterchev,
ZhiDe Deng,
Robert C. Basner,
Yaakov Stern,
Sarah H. Lisanby
Publication year - 2013
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.2712
Subject(s) - sleep deprivation , transcranial magnetic stimulation , psychology , functional magnetic resonance imaging , neuroplasticity , audiology , sleep (system call) , neuroscience , medicine , stimulation , cognition , computer science , operating system
We attempted to prevent the development of working memory (WM) impairments caused by sleep deprivation using fMRI-guided repetitive transcranial magnetic stimulation (rTMS). Novel aspects of our fMRI-guided rTMS paradigm included the use of sophisticated covariance methods to identify functional networks in imaging data, and the use of fMRI-targeted rTMS concurrent with task performance to modulate plasticity effects over a longer term.
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