Obstructive Sleep Apnea as a Risk Factor for Cerebral White Matter Change in a Middle-Aged and Older General Population
Author(s) -
Hyun Kim,
ChangHo Yun,
Robert J. Thomas,
Seung Hoon Lee,
Hyung Suk Seo,
Eo Rin Cho,
Seung Ku Lee,
Dae Wui Yoon,
Sooyeon Suh,
Chol Shin
Publication year - 2013
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.5665/sleep.2632
Subject(s) - medicine , polysomnography , obstructive sleep apnea , odds ratio , risk factor , dementia , confidence interval , population , sleep apnea , stroke (engine) , logistic regression , physical therapy , apnea , cardiology , mechanical engineering , disease , environmental health , engineering
Obstructive sleep apnea (OSA) contributes to the development of systemic hypertension, and hypertension strongly predicts the development of white matter change (WMC). Thus, it is plausible that OSA mediates WMC. The goal of the current study is to determine whether a contextual relationship exists between OSA and cerebral WMC.
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