A Mechanism for Upper Airway Stability during Slow Wave Sleep | Zendy

David G. McSharry | Zendy; Julian P. Saboisky | Zendy; Pam DeYoung | Zendy; Paul Matteis | Zendy; Amy S. Jordan | Zendy; John Trinder | Zendy; Erik Smales | Zendy; L Hess | Zendy; Mengshuang Guo | Zendy; Atul Malhotra | Zendy

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A Mechanism for Upper Airway Stability during Slow Wave Sleep

Author(s) -

David G. McSharry,

Julian P. Saboisky,

Pam DeYoung,

Paul Matteis,

Amy S. Jordan,

John Trinder,

Erik Smales,

L Hess,

Mengshuang Guo,

Atul Malhotra

Publication year - 2013

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.5665/sleep.2544

Subject(s) - genioglossus , anesthesia , polysomnography , slow wave sleep , obstructive sleep apnea , airway , medicine , sleep stages , apnea , sleep (system call) , cardiology , electroencephalography , psychiatry , computer science , operating system

The severity of obstructive sleep apnea is diminished (sometimes markedly) during slow wave sleep (SWS). We sought to understand why SWS stabilizes the upper airway. Increased single motor unit (SMU) activity of the major upper airway dilating muscle (genioglossus) should improve upper airway stability. Therefore, we hypothesized that genioglossus SMUs would increase their activity during SWS in comparison with Stage N2 sleep.

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